Patient tumor-OPDX-3D-2D-cell line visualization from McEvoy et al "Next-Generation Pediatric Cancer Models: Patient-Matched Orthotopic Xenografts, 3D Organoids, 2D Cultures, and Cell Lines for Identification of Therapeutic Vulnerabilities in Pediatric Solid Tumors"
Neuroblastoma Visualization from Human Tumor Atlas Pilot Project: single-cell/nucleus RNA-seq atlas of neuroblastoma (part of Human Tumor Atlas Network Consortium)
Rhabdomyosarcoma Visualization from Patel AG et al, The myogenesis program drives clonal selection and drug resistance in rhabdomyosarcoma. Dev Cell. 2022 May 23;57(10):1226-1240
Single-cell/nucleus RNA-sequencing data set from patient tumors and associated O-PDX tumors. Each data set is annotated based on disease classification.
Full characterization of each O-PDX sample is available from the Search O-PDX Samples view in the portal.
- Adrenocorticoid Carcinoma
- Alveolar (fusion-pos) rhabdomyosarcoma
- Clear cell sarcoma of the kidney
- Clear cell sarcoma of soft tissue
- Desmoplastic small round cell tumor (DSRCT)
- Embryonal (fusion-neg) rhabdomyosarcoma
- Embryonal sarcoma
- Epithelioid sarcoma
- Ewing sarcoma
- Gastrointestinal stromal tumor
- Germ cell tumor
- High grade sarcoma
- Infantile Filbrosarcoma
- Malignant Rhabdoid Tumor
- Neuroblastoma
- Osteosarcoma
- Retinoblastoma
- Spindle Cell Sarcoma
- Spindle/Sclerosing (MYOD1 Mutant) Rhabdomyosarcoma
- Synovial Sarcoma
- Undifferentiated Round Cell Sarcoma
- Wilms Tumor
This video below provides a step by step walkthrough of how to navigate the Visualization interface and features
Tip: Use fullscreen mode for better exploration of the visualization.