Select a disease from the dropdown or click on the data type to view.
Disease Somatic Mutations
View the most common somatic mutations in cohorts of patients and matched PDOX tumors and cell lines displayed in interactive oncoprints.
Chemical Sensitivity
Chemical sensitivity data (single-point, dose response, and combination therapies) for patient tumor and PDOX-derived cell lines.
Epigenetic Browsers
Epigenetic data includes whole genome bisulfite (WGBS) and ChIP-seq data for eight histone marks and CTCF, Brd4 and RNA PolII for a total of over 750 ChIP-seq libraries. The data have been integrated to define chromatin states using chromatin Hidden Markov Modeling.
sc/sn RNA-seq
Single-cell/nucleus RNA-sequencing data sets from patient tumors and associated O-PDX tumors. Samples are annotated based on histologic type, developmental state, and predicted cell cycle phase. Patient tumor datasets contain separate viewers for malignant nuclei (>111,000 nuclei) or non-malignant nuclei (>11,000 nuclei). O-PDX datasets contain a viewer for >100,000 cells
Methylation Classification
DNA methylation profiling was performed as part of the solid tumor Comprehensive METhylation (COMET) Blue Sky project, a collection of >4700 samples including patient tumors, Xenografts, and cell lines.