Childhood Solid Tumor Network

Resources & Models for Research and Discovery

The CSTN Data Portal provides access to orthotopic patient-derived xenograft models of childhood solid tumors and data.

The CSTN Data Portal is an innovative cloud-based data portal developed to stimulate basic research and speeding translation to the clinic. The portal allows researchers to explore various biological features of our pediatric O-PDX models, which provide both in vivo and in vitro systems to study mechanisms of disease origin, tumor progression and preclinical testing. Learn more

Disease Types

The vast diversity of the collected childhood solid tumors is represented in more than 150 O-PDX models, consisting of over 20 diagnoses, including neuroblastoma, rhabdomyosarcoma and rare tumors.

Search O-PDX Samples
Sample and Gene Search

Data on O-PDX models can be visualized and compared in this data portal. The interface allows both gene and sample level search and visualization. All O-PDX samples are also freely available on request.

Search Genes
Sample-Level Data

The models have been characterized and compared with the original patient tumor using various methods and assays including histology, electron microscopy, genomic sequencing, clonal analysis, and more.

Data Types