The CSTN Data Portal provides access to orthotopic patient-derived xenograft models of childhood solid tumors and data.
The CSTN Data Portal is an innovative cloud-based data portal developed to stimulate basic research and speeding translation to the clinic. The portal allows researchers to explore various biological features of our pediatric O-PDX models, which provide both in vivo and in vitro systems to study mechanisms of disease origin, tumor progression and preclinical testing. Learn more
The vast diversity of the collected childhood solid tumors is represented in more than 150 O-PDX models, consisting of over 20 diagnoses, including neuroblastoma, rhabdomyosarcoma and rare tumors.Search Disease Types
The models have been characterized and compared with the original patient tumor using various methods and assays including histology, electron microscopy, genomic sequencing, clonal analysis, and more.Review Data Types
Data on O-PDX models can be visualized and compared in this data portal. The interface allows both gene and sample level search and visualization. All O-PDX samples are also freely available on request.Search Samples & Genes